Sens (Basel) 2019, 19: 1-17 Kalus M-R, Lanyumba R, Lorenzo-Parodi N, Jochmann MA, Kerpen K, Hagemann U, Schmidt TC, Barcikowski S, Gkce B
SwissADME-based prediction of drug-likeness and ADMET parameters The selected compounds were comprehensively evaluated for their physicochemical properties, pharmacokinetic profiles, drug-likeness parameters, and medicinal chemistry characteristics through the SwissADME computational platform developed and maintained by the Molecular Modeling Group at the Swiss Institute of Bioinformatics ( o/w ) by combining physics-driven approaches such as iLOGP, which reduces the overfitting tendency, with data-centered models trained on extensive experimental measurements
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