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A 5 to 8 minute plasma half-life means that by the time subcutaneously injected DSIP is absorbed from the injection site, cleared through lymphatics into venous blood, and circulated, a very substantial fraction has already been enzymatically degraded
Laboratory studies have also reported changes in growth hormone receptor expression in tendon fibroblasts exposed to BPC-157, suggesting a role in connective-tissue signaling environments [5]
Because the peptide occurs naturally in human plasma (at roughly 200 ng/mL in young adults, declining to approximately 80 ng/mL by age 60), topical supplementation essentially restores youthful local concentrations in treated skin
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts Chang CH, Tsai WC, et al
Guang Yang, University of Maryland, College Park, United States Updates Copyright 2021 Huang, He, Makarcyzk and Lin
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