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Description

The main reason to be cautious with a 16-week plan is that there is no clinical subcutaneous evidence to guide the extension

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Real-world dosing and outcomes 6-month persister loss about 12-13% (Hankosky DOM 2025), broad-cohort about -9.8% (Adamidis Cureus 2026), telehealth completers near -23% (Duncan Obesity Pillars 2026)

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PMID 14527323

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