Minimum and maximum data for relevant treatment doses from PIONEER 9 and PIONEER 10 were used to define realistic ranges for efficacy and safety attribute levels, and additional hypothetical values were added within these ranges
Andrology, 11, 225-233
This does make sense to me though, given that the GLP-1s may tangle with our systems of reward, etc
If symptoms are severe, discuss with your provider whether a slightly lower dose or slower titration might reduce discomfort while still achieving your weight loss goals
Dipeptidyl dipeptidase-4 inhibitors These drugs, consisting primarily of sitagliptin, vildagliptin, linagliptin, saxagliptin, and alogliptin, enhance the effects of incretins by inhibiting dipeptidyl dipeptidase 4 (DPP-4), the enzyme responsible for their degradation