While Tirzepatide often produces greater total weight loss than AOD-9604 , it also carries a more complex side effect profile including nausea, vomiting, and gastrointestinal distress
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Breast milk is also high in choline, so breastfeeding the baby also depletes the mother of choline.[ref][ref] A US national survey showed that over 90% of the adult population doesnt meet the Adequate Intake (AI) recommendations for choline
What stood out most to me was that 45.3% of participants on the 12 mg dose achieved 30% or greater weight loss, a level historically associated with bariatric surgery
Biol Trace Elem Res 159(13):8798 Rijntjes E, Scholz PM, Mugesh G, Kohrle J (2013) Se- and se-based thiouracil and methimazole analogues exert different inhibitory mechanisms on type 1 and type 2 deiodinases