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Other Warnings for SEMALIX 3 TABLET Before taking SEMALIX 3 TABLET, inform your doctor if you: Have or have had pancreatic problems Have a history of diabetes-related vision problems (diabetic retinopathy) Are planning to undergo or have recently undergone surgery Experience severe and persistent abdominal pain Have low blood sugar (hypoglycaemia) Notice sudden changes in vision Have delayed gastric emptying (gastroparesis) Have gastrointestinal issues, such as severe vomiting, diarrhoea, or dehydration Have gallbladder problems Who should not take SEMALIX 3 TABLET SEMALIX 3 TABLET is not recommended for use if you: Have a personal or family history of medullary thyroid carcinoma (MTC) Have an endocrine disorder known as Multiple Endocrine Neoplasia syndrome type 2 (MEN2) Have type 1 diabetes Have developed diabetic ketoacidosis Drug - Drug interaction Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements

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Berberine activates the -catenin/TCF4 signaling pathway by down-regulating miR-106b to promote GLP-1 production by intestinal L cells