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However, when the semaglutide shortage ended in February 2025, some compounders and DTC platforms continued producing compounded GLP-1s, resulting in regulatory scrutiny and legal action from the FDA and semaglutide manufacturer Novo Nordisk
The substrate Z-L-arginine 4-methyl-7coumarinylamide was dissolved in HBSS at a concentration of 0.01 mg/mL, and sodium chenodeoxycholate was dissolved at a range of concentrations starting at 100 mg/mL
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Researchers following the regulatory trajectory should monitor the peptide regulatory landscape for updates as trial results become available
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