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In addition, because of differences in baseline characteristics between the groups, the analysis was performed post hoc with age, sex, and log(weight) as explanatory variables

reported outcomes are more plausibly indirect via recovery, routine adherence, and activity changes

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In this paper, we report five cryo-EM structures of two well-recognized multi-targeting agonists (tirzepatide and peptide 20) in complex with individual receptors and G s proteins