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Fat browning refers to the high plasticity of white fat cells, which can be transformed into beige fat cells with many similar morphological and functional characteristics to brown fat cells under the stimulation of exercise, cold exposure, adrenergic receptor stimulation, and other factors [83]
Patchy pigmentation (irregular splotches rather than uniform gradation) suggests inconsistent dosing or administration technique
We also look at when a combination treatment actually makes sense
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