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Metformin works by improving the bodys sensitivity to insulin, thereby reducing blood sugar production in the liver and increasing glucose uptake in the muscles
It helps regulate glycogen, which impacts energy levels
B12 and Premature Greying One area where B12s role is more clearly established is in premature greying grey hair that appears before age 20-30 (depending on ethnicity)
Its concentration is particularly high in mitochondria, where it protects respiratory chain complexes from oxidative stress (Wu et al., J Nutr 2004)
Symptoms include fatigue, pale skin, headaches, and mood changes
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