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In contrast, if RBCs were loaded with human hexokinase, they showed a doubled glycolytic activity, a normal hexose monophosphate pathway, and normal ATP and 2,3-BPG concentrations ( Furthermore, as the 2,3-BPG concentration decreases and hemoglobin affinity for O 2 increases, there is also an accumulation of reactive species of oxygen (ROS) due to the impaired RBCs antioxidant capability ( 3.3 Immunophilin-loaded RBCs Biagiotti et al

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It is important to point out that all groups of patients remarkably improved their oxidative stress condition

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Cyanocobalamin B-12 Injection USP 1000mcg/mL, 30mL Vial