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Nosemaglutide is designed as a once-weekly injection because its seven-day half-life maintains steady blood levels with that dosing schedule

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For follow-up therapy 2-3 ampoules are given per week

However, HE staining showed slight folding, shrinking and delamination of the basement membrane of seminiferous tubules in the rat testicular tissue, an increasing amount of sperm, insignificant damage to spermatogenesis, a lack of mature spermatogenic cells, a slightly disordered and sparse cell arrangement with 35 layers and visible cell polarity in groups C and D