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[6] Because NAD + -dependent enzymes are involved in DNA repair, protein deacetylation, stress responses, mitochondrial function, and cellular signaling, NNMT-related changes in NAD + availability should be interpreted in a pathway-specific manner rather than as a simple beneficial-or-harmful binary

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The lack of adequate vitamin B12 from sources such as meat, eggs, and dairy, can lead to deficiencies causing anemia, intestinal issues, and other medical conditions

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