Buse JB, Wexler DJ, Tsapas A, Rossing P, Mingrone G, Mathieu C, DAlessio DA, Davies MJ
A liposome is not a fixed, stable object: it is a microscopic fat droplet that naturally tends to merge with other liposomes, fall apart, or leak its contents, particularly during storage
Orphan Drug Exclusivity: Seven Years of Protection That Sits Outside the Patent System Entirely Orphan drug exclusivity, granted for drugs approved to treat rare diseases affecting fewer than 200,000 patients in the U.S., provides seven years of marketing exclusivity that runs independently of any patent
The label carries a boxed warning about thyroid C-cell tumors based on rodent findings
Originally approved for conditions like heart failure, hypertension, and certain cases of hyperaldosteronism (where the body produces too much of a hormone called aldosterone), it has since found its way into the treatment of acne, hair loss , and even hormonal imbalances