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In: Li K (ed) Neuroproteomics

doi: 10.1113/EP090305 88 AguerCColinSMcCoinTThrushABOno-MooreKMcPhersonRet al

[12] Observations in ob/ob mice, Zucker rats, knockout mice, or mouse-derived adipocyte systems should therefore remain explicitly labeled as rodent or preclinical findings

Chronic psychological stress leads to continuous sympathetic nervous system activation (the "fight or flight" response), which elevates cortisol and drives visceral fat storage around the organs