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Classic examples include native GLP-1, which has a plasma half-life of approximately 2 minutes and required continuous infusion in early studiesan impractical route for chronic therapyyet was subsequently transformed into a once-weekly therapeutic through lipidation and albumin-binding strategies (Drucker, 2018)

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The pigment can be an inorganic sunscreen (such as titanium dioxide) or a colorant that is blended with alumina platelets and then often coated with some kind of silicone (such as triethoxycaprylylsilane)