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In ME/CFS, SNPs in TLR signalling pathways, the complement cascade, and cytokines have been identified (74, 496)

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For ACF, the existing strategies mainly include chemoprevention (such as the use of drugs like aspirin and celecoxib), dietary modification (increasing fiber intake and reducing the consumption of red meat and fat), as well as preventing the occurrence and development of colorectal cancer through endoscopic monitoring and the resection of high-risk lesions 49,50