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There has been an increasing amount of evidence suggesting that CAP can affect the composition, abundance, and function of the gut microbiota

6.2 Challenges faced The half-life of natural PYY is extremely short (only about 812 minutes) (170) and requires frequent drug use, which seriously limits its clinical feasibility

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De Marinis YZ, Salehi A, Ward CE et al (2010) GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis