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It is important to remember that GLP-1 RAs are only one piece of the puzzle and should always be recommended in conjunction with diet, exercise and lifestyle modifications
In a large retrospective cohort study, GLP-1RAs significantly improve metabolic outcomes in individuals with MASLD, it can reduce major adverse cardiovascular events, all-cause mortality, and hospitalizations due to heart failure among individuals diagnosed with type 2 diabetes ( 2.3 Crosstalk between GLP-1 and and the gut microbiome 2.3.1 GLP-1 modulates the gut microbiota Emerging evidence indicates a bidirectional regulatory relationship between GLP-1RAs and the gut microbiota (Zhang et al., 2018
Specifically, first-year discontinuation rates are about 45% for patients with T2DM and 65% for those without (Rodriguez et al., 2025)
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While you might have heard of Ozempic , you might not be familiar with how it works and all its forms
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