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Role of GLP-1 in Metabolic Regulation GLP-1 is known for its multifaceted role in metabolic regulation, extending beyond insulin secretion

Most private providers follow criteria broadly aligned with NICE guidance: A BMI of 30 or above , or A BMI of 37 or above alongside a weight-related comorbidity such as type 2 diabetes, hypertension, or obstructive sleep apnoea Some providers may consider patients with a BMI slightly below these thresholds at clinical discretion

GLP-1 is a natural hormone produced in the gut after eating

The naturally occurring phytocannabinoids can be extracted from the plant and isolated, or they could be synthesized in a lab

Understanding which neurotransmitter system is primarily affected can help guide treatment decisions, something we will explore in the strategies section below