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Progressive depletion of cellular glutathione is also used as a mechanism by many viruses to control their replication cycle during infection.

Allerdings relativiert die niedrigere systemische Bioverfgbarkeit diesen Vorteil: Wenn ein geringerer Anteil der Dosis systemisch ankommt, wird pro erzieltem systemischem Effekt unter Umstnden mehr Substanz bentigt

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The options have historically been limited: Minoxidil (with its side effect profile), Finasteride (with its systemic hormonal effects), expensive PRP injections, or hair transplants