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Plasma concentrations of L-citrulline and L-arginine were significantly elevated immediately post-exercise and 30 minutes post-exercise following supplementation

Clinical studies have generally shown good tolerance at recommended doses, with most adverse effects being mild and transient

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The review confirmed that BPC-157 activates VEGFR2 and drives nitric oxide synthesis via the Akt-eNOS axis, promoting angiogenesis, fibroblast activity, and neuromuscular stabilisation