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A meta-analysis of 17 randomized controlled trials found that L-carnitine supplementation was associated with improvements in several markers of cardiac function in patients with chronic heart failure
Initially developed as glucose-lowering therapies, both classes have shown impressive cardiovascular and kidney-protective effects [17,18]
Exception : Saxagliptin has been associated with an increased risk of hospitalisation for heart failure (SAVOR-TIMI 53 trial), and should be avoided in patients with established HF or high HF risk
However, for patients with Crohn's disease, distinguishing between medication side effects and disease flare becomes challenging, potentially delaying appropriate management of IBD exacerbation
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