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Neurological Function : B12 helps maintain the myelin sheath that protects nerves and enables proper signalling between brain and body

Typical side effects include nausea, headache, facial flushing, and localized hyperpigmentation, generally mild to moderate and self-limiting

Results KAT6A mutations cause a decrease in histone H3 lysine 23 (H3K23) acetylation in human cells and mice To determine the effects of mutation of the KAT6A gene on histone acetylation, we generated human HEK293T cells carrying six different KAT6A variants observed in individuals with ARTHS using CRISPR/Cas9 and homology-directed repair (Tables S1, S2, and S3)

J Nutr Intermed Metab

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