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Avoid areas with surgical scars, burn marks, heavy stretch marks, or previously injured tissue

I like to say that medications are like flying a plane

Hetherington A, Ranson S

No clinically relevant difference in the pharmacokinetics of TRESIBA was identified in a study comparing healthy subjects and subjects with kidney impairment including subjects with end stage kidney disease [see CLINICAL PHARMACOLOGY ]

SIDE EFFECTS Melanotan I (Afamelanotide) has a more favorable side effect profile than the highly non-selective Melanotan II (MT-2), but users must be aware of potential reactions, particularly related to skin changes