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PMID: 56 ChenPLinLXuXZhangZCaiWShaoZet al
Specifically, NAC is a derivative of the amino acid L-cysteine, an essential precursor used by the body to produce glutathione
Digestive enzymes 4
With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
A previous report suggested that mitochondrial dicarboxylate and 2-oxoglutarate carriers may additionally transport glutathione 32 , a finding later disproved 33
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