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Gastroenterology 112 (4SUPPL):A925

[11] [12] Practical strategies for managing hunger include: Eating at consistent times to regulate ghrelin secretion and establish predictable hunger patterns Adequate hydration , as a practical checkthirst is sometimes misinterpreted as hunger Mindful eating practices , including eating slowly and without distractions, which enhance satiety signals Sufficient sleep (79 hours for most adults), as sleep deprivation increases ghrelin and decreases leptin [8] [9] Stress management , since cortisol elevation can dysregulate appetite hormones Including a source of protein and fibre at each meal to maximise satiety duration For individuals attempting weight management, gradual calorie reduction (approximately 600 kcal daily deficit, in line with NICE and NHS guidance) is more sustainable than severe restriction and less likely to trigger excessive hunger or metabolic adaptation

Does semaglutide work

Getting the basics right, hydration, fiber, and movement, resolves the majority of constipation cases without additional intervention

And, like other medications, those side effects can be more serious when mixed with other health issues