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Synthesis Method: Synthesized chemically as a small molecule with peptide-like properties to ensure precise molecular structure and high activity levels
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Pre-treatment of cells with membrane-permeable inorganic or organic polysulfides, confirmed to generate endogenous GSSH (Extended Data Fig
Additionally, a pilot randomized trial reported that short-term combination treatment with beinaglutide and metformin was more effective than metformin monotherapy in lowering body weight, improving insulin sensitivity, and reducing androgen excess in women living with PCOS and obesity [33]
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