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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
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Most patients see noticeable weight increases within 8-12 weeks, with 50% of lost weight returning by month 12
This process enables the endometrium to acquire a receptive phenotype, promoting embryo implantation and pregnancy maintenance by providing a nutritive and immunoprivileged environment ( Figure 1 Concurrently, during decidualization, the differentiation of stromal cells is accompanied by significant metabolic changes, with glucose serving as a primary energy source ( Aberrant glucose metabolism, characterized by dysregulated glucose uptake or glycolysis in human endometrial stromal cells (hESCs), contributes to decidualization deficiencies and subsequent embryo implantation failure ( Figure 1 )
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