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Long-acting, subcutaneously administered, PYY RA are undergoing early phase clinical trials as obesity treatments either alone or in combination with GLP-1 RA (Table 1, NCT02568306 and NCT03574584)
Results are summarised in Supplementary Figs
It is not the molecule that decides but the dose and the pace of weight loss
That means generic pharmaceutical companies can launch versions of semaglutide, which could lead to prices falling by 65 per cent
GLP-1s are the biological accelerant to an existing sober curious moderation trend, thats been driven by social shifts and cost of living challenges, says Tom Ellis, CEO of innovation consultancy, Brand Genetics
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