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Glutathione does reduce oxidative stress markers (MDA, 4-HNE) during acute alcohol exposure, which theoretically lowers hepatocyte damage
Glutathione is one of the most important antioxidants in the body, helping to remove toxins and free radicals, and supporting the immune system
Persistent diarrhea beyond the titration period warrants evaluation and potential dose adjustment
A similar scenario has in fact been reported recently in an alcoholic liver disease model in which long-term alcohol consumption activated NF-B in Kupffer cells, whereas NF-B activation in hepatocytes was inhibited 45
doi:10.1093/humupd/dmx001
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