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Qsymia (phentermine and topiramate) is an FDA-approved extended-release weight loss medication

A longer overnight eating break is not appropriate for everyone, including some people with diabetes or on blood-sugar medications, those who are pregnant or breastfeeding, and anyone with a history of disordered eating

Obesity 30 , 1113 (2022)

Neeland, Linge, and Birkenfeld (2024), writing in Diabetes, Obesity and Metabolism , conclude that skeletal muscle changes with GLP-1 receptor agonist treatment appear adaptive: reductions in muscle volume are commensurate with what is expected given aging, disease status, and weight loss achieved, and improvements in insulin sensitivity and muscle fat infiltration likely contribute to improved muscle quality

V (weeks 190 to 210)