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Patients taking other B vitamin supplements should disclose this to their provider to avoid excessive intake

The review confirmed that GHK-Cu stimulates blood vessel and nerve outgrowth, increases collagen, elastin, and glycosaminoglycan synthesis, and supports dermal fibroblast function

Focus on assessing GI tolerance, injection site reactions, and baseline appetite changes

List of the abbreviations PRP: Platelet-Rich Plasma MRI: Magnetic Resonance Imaging ACL: Anterior Cruciate Ligament NRS: Numerical Rating Scale KOOS: Knee Injury and Osteoarthritis Outcome Score TLKSS: Tegner Lysholm Knee Scoring Scale VAS: Visual Analog Scale SF-36: RAND-36 (Short Form 36) IKDC: International Knee Documentation Committee IL: Interleukin TGF-: Transforming Growth Factor Beta PDGF: Platelet-Derived Growth Factor IGF: Insulin-like Growth Factor VEGF: Vascular Endothelial Growth Factor EGF: Epidermal Growth Factor -FGF: Basic Fibroblast Growth Factor NSAIDs: Non-steroidal anti-inflammatory Drugs Authors Contributions Both authors AEZ and JY equally contributed to the project

If you suspect you have experienced a side effect from any medicine or research chemical, you can report it to the MHRA via the Yellow Card Scheme (yellowcard.mhra.gov.uk)