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Specifically, retatrutide is intended to activate the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor a combination that distinguishes it from existing approved therapies such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 receptor agonist)

Also, there is no widely available generic version of these branded weight loss injections in the UK

Clinical studies, such as the SURMOUNT trials, showed that significant weight loss often occurs over the course of several months, with continued progress up to 72 weeks

FDA Access Data+2New England Journal of Medicine+2 In both cases, semaglutide is meant to be used alongside lifestyle changes such as a reduced-calorie diet and increased physical activity

To amplify Wegovy's impact, incorporate a reduced-calorie diet and increased physical activity into your routine