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Disclosure statement All authors are employees of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA, which provided funding to support M.A.C

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But, supplements can fill gaps, helping those with deficiencies or increased needs

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Bhattacharjee, P

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Schwappach for critical reading of the manuscript

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Mitochondria generate superoxide (O 2 - ), rapidly converted to hydrogen peroxide (H 2 O 2 ) by superoxide dismutases (SOD1 in cytosol/intermembrane space, SOD2 in the matrix, and SOD3 extracellularly) (Yang et al., 2020)

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