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How long to stay on semaglutide is a question many people ask, and the answer for most is indefinitely, at a maintenance dose that preserves results while minimizing side effects
Presentations at the most recent ADA scientific sessions in 2024 included discussions of clear benefits to reduce liver fat in MASH (formerly called NAFLD) with tirzepatide (Loomba, NEJM, 2024) and a phase 2 trial with the triagonist (GLP-1/GIP/Glucagon), retatrutide (Sanyal, Nature Medicine, 2024)
Depending on your personal health profile, there could be benefits to taking berberine and semaglutide together, such as improved blood sugar control
But unfortunately, as we age, it's common to notice unwelcome changes in our bodies, whether they be changes to your skeletal muscles or how you manage your weight
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