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No one doubts that they reduce insulin resistance, effectively treating type 2 diabetes
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The condition is characterised by transmural inflammation meaning it affects the full thickness of the bowel wallwhich can lead to complications including strictures, fistulas, and abscesses
The peptide's anorexigenic effects appear mediated primarily through MC4R, as studies using MC4R-specific agonists produced similar appetite-suppressing effects
Nephrology 29 , 457469 (2024)
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