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In a Phase 2b study in people with type 2 diabetes and obesity over 54 weeks, treatment with cotadutide at doses of 100-300 g daily improved some non-invasive markers of NAFLD such as transaminase levels, the FIB-4 index, fatty liver disease fibrosis score (NFS) and fatty liver index (FLI) but fatty liver disease was not assessed directly with liver biopsy

This suggests that while lifestyle is vital, the metabolic support provided by the medication can significantly boost the chances of success

AARP Hearing Center Health Benefits of GLP-1s Beyond Weight Loss Popular medications like Ozempic and Wegovy can do more than just help shed pounds The famed quartet of diabetes and weight-loss drugs Ozempic, Wegovy, Zepbound and Mounjaro are well-known for their ability to help people shed pounds, in some cases up to 20 percent of body weight