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Human embryonic kidney (HEK) 293T cells recombinantly expressing human GIPR or cynomolgus monkey GIPR and Chinese hamster ovary (CHO) cells expressing rat or mouse GIPR were used to measure cyclic adenosine monophosphate (cAMP) accumulation

The mechanism of action involves mimicking the naturally occurring hormone GLP-1, which is released from the intestine after eating

Both ended weight-loss GLP-1 coverage effective January 1, 2025, but the scope differs

Tracking results provides motivation and data