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Animal studies have shown that semaglutide may cause congenital disabilities, low birth weight and increased risk of miscarriage, although these effects have not been thoroughly studied in humans

When semaglutide burping is a warning sign Most semaglutide-related burping is benign

Participant characteristics by baseline incretin effect While all participants ( n = 30) had a 2-hour glucose level 120 mg/dL at baseline, 17 of the 30 participants (57%) maintained a 2-hour glucose level 120 mg/dL at the follow-up OGTT, with 10 of the 17 exhibiting impaired glucose tolerance (IGT) and 1 exhibiting overt diabetes

In a Phase IIb study by Steidle et al

The rate of weight loss tends to be higher in the initial months as the body adjusts to the medication and the effects on appetite and metabolism take hold