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The predominant RNS is nitric oxide radical (NO ) [36], formed in biological tissues from the oxidation of L-arginine to citrulline by nitric oxide synthase [37, 38], and precursor of other two RNS, the peroxynitrite (ONOO ), and the nitrogen dioxide radical ( NO 2 ) (Fig
J Am Chem Soc 137:1427514280
However, interpreting the health benefits of selenium against radiotherapy as the clinical validation of the radio-modulating activity of seleno-GPxs may be misleading, since selenium can manifest its beneficial effects through various mechanisms including but not limited to seleno-GPxs
This product is not for human consumption, medical, or therapeutic use
Elderly patients represent another high-risk population in NORA settings
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