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However, knowledge of the normal ranges for all redox metabolites in accessible bodily liquids, such as blood, in healthy human populations has been lacking, largely because of a lack of methodology to assess full redox profiles in a high throughput manner from large population materials
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In that study, UA treatment increased the mRNA and protein expression of Nrf2 and three Nrf2-responsive genes, including the g-glutamate-cysteine ligase catalytic subunit, heme oxygenase-1, and NQO1, which are oxidation-related genes involved in redox homeostasis
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