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296,297,298 Typically, NF-B binds to its inhibitor IB in the cytoplasm
GLP-1RA could not only facilitate the M2 polarization of microglia through both direct and indirect pathways, but also modulate the quantity and function of T cell subtypes, including CD4, CD8, and regulatory T cells, resulting into the inhibition of inflammatory responses and the promotion of neuronal regeneration through interleukin-10 secretion
These might include additive, synergistic, or antagonistic effects that cannot be reliably predicted without dedicated pharmacokinetic and pharmacodynamic studies