Others maintain benefits with less frequent treatments
Figure 1 Iron metabolism is central to the regulation of ferroptosis, as iron plays dual roles in cellular physiology: it is essential for oxygen transport, DNA synthesis, and enzymatic reactions, yet its dysregulation drives pathological lipid peroxidation (Rochette, 2022)
Due to the lack of oxidation, the fatty acids accumulate in the liver, skeletal muscle, and heart resulting in hepatic steatosis, myopathy, and cardiomyopathy, respectively
However, barrier function is not solely regulated by ECs, pericytes, astrocyte-processes and basement membrane
An anti-fade mounting medium was applied, and coverslips were placed to seal the samples