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Our previous study, BARI-OPTIMISE, selectively recruited participants with suboptimal weight loss after MBS who also had a blunted meal-stimulated GLP-1 response, based on observational study data correlating higher native postprandial GLP-1 levels to higher %WL after MBS

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Counsel patients regarding the potential risk for MTC with the use of RYBELSUS and inform them of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness)