These metabolites, together with mitochondrial DNA released into the cytoplasm, activate the NLRP3 inflammasome and cGAS-STING pathways, driving the release of IL-1 and type I interferons
Other signs may include shortness of breath, pale skin, stomach problems, such as constipation, diarrhea or gas, or nerve problems, like muscle weakness or tingling in fingers or toes. Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says
Hydration: Drink plenty of water to help the IV fluids circulate
J Urol 2015
Possible Joint and Cartilage Benefits Early research has explored whether it may help stimulate cartilage repair