Beyond managing weight and blood sugar, emerging research suggests these medications may offer protective benefits for the heart and kidneys
While GLP-1s and similar peptides famously suppress appetite, reduce blood sugar, and cause weight loss, a growing body of research suggests they might also do much more: curb inflammation all over your body, increase mitochondria in skeletal muscle to give you more energy and help you build strength, and reduce the risk of conditions ranging from Alzheimers to heart disease to alcohol use disorder
While the results of this article do not exclude a direct action of metformin in the liver, they suggest that the first site of metformin action is the gut, via gut-hepatic crosstalk, and that it may play a role in the control of hepatic glucose production, integrating the site and mechanism of metformin action
If you are using a GLP-1 medication, you want strains that are specifically researched for metabolic health and digestive comfort
92,93 The transamination product of Asp, asparagine (Asn), is more permeable than Asp, but when cellular asparaginase activity is inhibited, Asn cannot be converted to Asp