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Tirzepatide 10 mg resulted in a loss of nearly 8 more pounds than semaglutide 2 mg Tirzepatide 5 mg resulted in a loss of almost 4 more pounds than semaglutide 1 mg When compared to a placebo, both drugs showed an increased risk of side effects, including gastrointestinal problems such as nausea, vomiting, and diarrhea

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Neurosciences 20 , 107114 (2015)