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In the offspring, reduced growth and fetuses with visceral (heart blood vessels) and skeletal (cranial bones, vertebra, ribs) abnormalities were observed at the human exposure

It covers three agents: liraglutide, semaglutide, and tirzepatide

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Originally approved in 2005 Trusted Source PubMed Central Go to source , GLP-1 analogs produced significant and beneficial weight loss in type 2 diabetes patients