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Melatonin Melatonin, a hormone synthesized primarily by the pineal gland and locally in skin cells, plays a critical role in protecting melanocytes from oxidative stress by acting as a potent antioxidant and modulating cellular defense mechanisms 196
O., Garla, L
Furthermore, studies performed in endothelial cells, Kaposis sarcoma-associated herpesvirus (KSHV)-transformed cancer cells and several normal fibroblast or epithelial cell lines reported a similar effect of asparagine on supporting cell survival and protein translation after glutamine deprivation 44,49,50
Abstract Cells are exposed to oxidative stress and reactive metabolites every day
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